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KIF14


Official Full Name
kinesin family member 14
Organism
Homo sapiens
Gene ID
9928
Background
This gene encodes a member of the kinesin-3 superfamily of microtubule motor proteins. These proteins are involved in numerous processes including vesicle transport, chromosome segregation, mitotic spindle formation, and cytokinesis. In human HeLa-S3 and 293T cells, this protein is localized to the cytoplasm during interphase, to the spindle poles and spindle microtubules during mitosis, and to the midbody during cytokinesis. An internal motor domain displays microtubule-dependent ATPase activity, consistent with its function as a microtubule motor protein. Knockdown of this gene results in failed cytokinesis with endoreplication, which results in multinucleated cells. This gene has been identified as a likely oncogene in breast, lung and ovarian cancers, as well as retinoblastomas and gliomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015]
Synonyms
MKS12; MCPH20

Cat.No. Product Name Price
SHH324999 shRNA set against Human KIF14 (NM_014875.2) Inquiry
SHH325003 shRNA set against Mouse KIF14 (NM_001081258.1) Inquiry
SHL196320 shRNA set against Mouse Kif14(NM_001081258.1) Inquiry
SHW009950 shRNA set against Danio rerio KIF14 (NM_001044976) Inquiry
Cat.No. Product Name Price
MiUTR1M-06304 KIF14 miRNA 3'UTR clone Inquiry
MiUTR3H-11768 KIF14 miRNA 3'UTR clone Inquiry
CDCB171425 Danio rerio KIF14 ORF Clone (NM_001044976) Inquiry
CDCB183092 Rabbit KIF14 ORF clone (XM_002717661.2) Inquiry
CDCL124125 Human Kif14 ORF clone (NM_001081258.1) Inquiry
CDCS413810 Human KIF14 ORF Clone (BC113742) Inquiry
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