Pages
Products

KIAA1128


Official Full Name
ATRX chromatin remodeler
Organism
Homo sapiens
Gene ID
546
Background
The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations in this gene are associated with X-linked syndromes exhibiting cognitive disabilities as well as alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2017]
Synonyms
ATRX; JMS; XH2; XNP; MRX52; RAD54; RAD54L; ZNF-HX

Cat.No. Product Name Price
SHH079283 shRNA set against Mouse Gcap14(NM_027045.1) Inquiry
SHH079301 shRNA set against Mouse Gcap14(NM_028407.3) Inquiry
SHH138053 shRNA set against Human KIAA1128(NM_018999.2) Inquiry
SHH290581 shRNA set against Human FAM190B (NM_018999.2) Inquiry
SHH299910 shRNA set against Mouse Gcap14 (NM_028407.3) Inquiry
SHW003295 shRNA set against Chicken CCSER2 (NM_001199508) Inquiry
Cat.No. Product Name Price
CDFG002171 Human FAM190B cDNA Clone(NM_018999.2) Inquiry
CDFL004936 Mouse Gcap14 cDNA Clone(NM_028407.3) Inquiry
MiUTR1H-05245 FAM190B miRNA 3'UTR clone Inquiry
MiUTR1M-04968 GCAP14 miRNA 3'UTR clone Inquiry
MiUTR1M-04969 GCAP14 miRNA 3'UTR clone Inquiry
CDCB164770 Chicken CCSER2 ORF Clone (NM_001199508) Inquiry
CDCB183396 Rabbit CCSER2 ORF clone (XM_008274322.1) Inquiry
CDCL110937 Mouse Gcap14 ORF clone (NM_028407.3) Inquiry
CDCL110939 Human Gcap14 ORF clone (NM_027045.1) Inquiry
CDCR063036 Human FAM190B ORF clone (NM_018999.2) Inquiry
CDCS418549 Human FAM190B ORF Clone (BC030528) Inquiry
Quick Inquiry