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KDELR1


Official Full Name
KDEL endoplasmic reticulum protein retention receptor 1
Organism
Homo sapiens
Gene ID
10945
Background
Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product. [provided by RefSeq, Jul 2008]
Synonyms
ERD2; HDEL; PM23; ERD2.1

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SHL193825 shRNA set against Human KDELR1(NM_006801.2) Inquiry
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SHL193890 shRNA set against Mouse Kdelr1(NM_133950.2) Inquiry
Cat.No. Product Name Price
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MiUTR1H-05185 KDELR1 miRNA 3'UTR clone Inquiry
MiUTR1M-06291 KDELR1 miRNA 3'UTR clone Inquiry
MiUTR1R-02854 KDELR1 miRNA 3'UTR clone Inquiry
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CDCL123563 Human Kdelr1 ORF clone (NM_133950.2) Inquiry
CDCR293734 Human KDELR1 ORF Clone(NM_006801.2) Inquiry
CDCR370434 Rat Kdelr1 ORF Clone(NM_001017385.1) Inquiry
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