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KAZALD1


Official Full Name
Kazal type serine peptidase inhibitor domain 1
Organism
Homo sapiens
Gene ID
81621
Background
This gene encodes a secreted member of the insulin growth factor-binding protein (IGFBP) superfamily. The protein contains an insulin growth factor-binding domain in its N-terminal region, a Kazal-type serine protease inhibitor and follistatin-like domain in its central region, and an immunoglobulin-like domain in its C-terminal region. Studies of the mouse ortholog suggest that this protein may function in bone development and bone regeneration. This gene is hypomethylated and over-expressed in high-grade glioma compared to low-grade glioma, and thus the hypomethylated gene may be associated with cell proliferation and the shorter survival of patients with high-grade glioma. It is also one of numerous genes found to be deleted in a novel 5.54 Mb interstitial deletion, which is associated with multiple congenital anomalies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Synonyms
BONO1; FKSG28; FKSG40; IGFBP-rP10

Cat.No. Product Name Price
SHH322511 shRNA set against Human KAZALD1 (NM_030929.4) Inquiry
SHH322515 shRNA set against Mouse KAZALD1 (NM_178929.4) Inquiry
SHH322519 shRNA set against Rat KAZALD1 (NM_001033064.1) Inquiry
SHL187350 shRNA set against Rat Kazald1(NM_001033064.1) Inquiry
SHL187590 shRNA set against Mouse Kazald1(NM_178929.4) Inquiry
Cat.No. Product Name Price
CDFR004211 Rat Kazald1 cDNA Clone(NM_001033064.1) Inquiry
MiUTR1M-06196 KAZALD1 miRNA 3'UTR clone Inquiry
MiUTR1R-02767 KAZALD1 miRNA 3'UTR clone Inquiry
MiUTR3H-10478 KAZALD1 miRNA 3'UTR clone Inquiry
CDCB182649 Rabbit KAZALD1 ORF clone (XM_002718621.2) Inquiry
CDCR275396 Mouse Kazald1 ORF Clone(NM_178929.4) Inquiry
CDCR371237 Rat Kazald1 ORF Clone(NM_001033064.1) Inquiry
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