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KANK1


Official Full Name
KN motif and ankyrin repeat domains 1
Organism
Homo sapiens
Gene ID
23189
Background
The protein encoded by this gene belongs to the Kank family of proteins, which contain multiple ankyrin repeat domains. This family member functions in cytoskeleton formation by regulating actin polymerization. This gene is a candidate tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder. A t(5;9) translocation results in fusion of the platelet-derived growth factor receptor beta gene (PDGFRB) on chromosome 5 with this gene in a myeloproliferative neoplasm featuring severe thrombocythemia. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2014]
Synonyms
KANK; CPSQ2; ANKRD15

Cat.No. Product Name Price
SHH322347 shRNA set against Human KANK1 (NM_153186.4) Inquiry
SHH322351 shRNA set against Mouse KANK1 (NM_181404.5) Inquiry
SHH322355 shRNA set against Rat KANK1 (NM_001037197.2) Inquiry
SHW004501 shRNA set against Chicken KANK1 (NM_001293232) Inquiry
Cat.No. Product Name Price
CDFL006393 Mouse Kank1 cDNA Clone(NM_181404.5) Inquiry
CDFR004486 Rat Kank1 cDNA Clone(NM_001037197.2) Inquiry
MiUTR1M-01484 KANK1 miRNA 3'UTR clone Inquiry
MiUTR3H-09395 KANK1 miRNA 3'UTR clone Inquiry
MiUTR3H-09396 KANK1 miRNA 3'UTR clone Inquiry
CDCB165976 Chicken KANK1 ORF Clone (NM_001293232) Inquiry
CDCB181764 Rabbit KANK1 ORF clone (XM_008256064.1) Inquiry
CDCH016038 Human KANK1 ORF clone(NM_015158.3) Inquiry
CDCL122539 Mouse Kank1 ORF clone (NM_181404.5) Inquiry
CDCR371526 Rat Kank1 ORF Clone(NM_001037197.2) Inquiry
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