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jag2b


Official Full Name
jagged canonical Notch ligand 2b
Organism
Danio rerio
Gene ID
140422
Background
Predicted to enable Notch binding activity and calcium ion binding activity. Acts upstream of or within several processes, including exocrine pancreas development; hematopoietic stem cell differentiation; and ventral spinal cord development. Predicted to be located in membrane. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane. Is expressed in several structures, including anterior neural rod; digestive system; mesoderm; nervous system; and trunk. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy. Orthologous to human JAG2 (jagged canonical Notch ligand 2). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
jag2; serB; zgc:152855

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