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ITPR3

Official Full Name
inositol 1,4,5-trisphosphate receptor type 3
Organism
Homo sapiens
GeneID
3710
Background
This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth. [provided by RefSeq, Aug 2010]
Synonyms
IP3R; CMT1J; IP3R3; IP3R-3;

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