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IRF4


Official Full Name
interferon regulatory factor 4
Organism
Homo sapiens
Gene ID
3662
Background
The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010]
Synonyms
MUM1; LSIRF; SHEP8; NF-EM5

Cat.No. Product Name Price
SHH320621 shRNA set against Mouse IRF4 (NM_013674.1) Inquiry
SHH320625 shRNA set against Rat IRF4 (NM_001106108.1) Inquiry
SHL180834 shRNA set against Mouse Irf4(NM_013674.1) Inquiry
SHW004815 shRNA set against Chicken IRF4 (NM_204299) Inquiry
Cat.No. Product Name Price
CDCL121603 Mouse Irf4 ORF clone (NM_013674.1) Inquiry
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CDFR005869 Rat Irf4 cDNA Clone(NM_001106108.1) Inquiry
MiUTR1M-06099 IRF4 miRNA 3'UTR clone Inquiry
CDCB166290 Chicken IRF4 ORF Clone (NM_204299) Inquiry
CDCB188393 Rabbit IRF4 ORF clone (XM_002721631.2) Inquiry
CDCR372879 Rat Irf4 ORF Clone(NM_001106108.1) Inquiry
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