Pages
Products

IL21R


Official Full Name
interleukin 21 receptor
Organism
Homo sapiens
Gene ID
50615
Background
The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
Synonyms
NILR; CD360; IMD56

Cat.No. Product Name Price
SHH318705 shRNA set against Mouse IL21R (NM_021887.2) Inquiry
SHH318701 shRNA set against Human IL21R (NM_021798.3) Inquiry
SHH318709 shRNA set against Rat IL21R (NM_001012469.1) Inquiry
SHL134778 shRNA set against Rat Il21r(NM_001012469.1) Inquiry
SHW001289 shRNA set against Chicken IL21R (NM_001030640) Inquiry
Cat.No. Product Name Price
CDFL006164 Mouse Il21r cDNA Clone(NM_021887.2) Inquiry
CDFR002689 Rat Il21r cDNA Clone(NM_001012469.1) Inquiry
MiUTR1R-02641 IL21R miRNA 3'UTR clone Inquiry
MiUTR3H-07617 IL21R miRNA 3'UTR clone Inquiry
MiUTR3H-07618 IL21R miRNA 3'UTR clone Inquiry
MiUTR3H-07619 IL21R miRNA 3'UTR clone Inquiry
CDCB162764 Chicken IL21R ORF Clone (NM_001030640) Inquiry
CDCL120459 Human IL21R ORF clone (NM_181079.4) Inquiry
CDCL184849 Rat IL21R ORF clone(NM_001012469.1) Inquiry
CDCR383032 Mouse Il21r ORF Clone(NM_021887.2) Inquiry
CDCS415361 Human IL21R ORF Clone (BC004348) Inquiry
Quick Inquiry