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IVD

Official Full Name
isovaleryl-CoA dehydrogenase
Organism
Homo sapiens
GeneID
3712
Background
Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017]
Synonyms
IVDH; ACAD2;

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