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ITGA4


Official Full Name
integrin subunit alpha 4
Organism
Homo sapiens
Gene ID
3676
Background
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Synonyms
IA4; CD49D

Cat.No. Product Name Price
SHH321197 shRNA set against Human ITGA4 (NM_000885.4) Inquiry
SHH321201 shRNA set against Mouse ITGA4 (NM_010576.3) Inquiry
SHH321205 shRNA set against Rat ITGA4 (NM_001107737.1) Inquiry
SHL181488 shRNA set against Human ITGA4(NM_000885.4) Inquiry
SHL181506 shRNA set against Mouse Itga4(NM_010576.3) Inquiry
Cat.No. Product Name Price
CDFH009427 Human ITGA4 cDNA Clone(NM_000885.4) Inquiry
CDFR007378 Rat Itga4 cDNA Clone(NM_001107737.1) Inquiry
MiUTR1H-05021 ITGA4 miRNA 3'UTR clone Inquiry
MiUTR1M-06134 ITGA4 miRNA 3'UTR clone Inquiry
CDCB156676 Cynomolgus ITGA4 ORF clone Inquiry
CDCB190142 Rabbit ITGA4 ORF clone (XM_002712227.2) Inquiry
CDCL184973 Human ITGA4 ORF clone(NM_000885.4) Inquiry
CDCL184974 Rat ITGA4 ORF clone(NM_001107737.1) Inquiry
CDCS405973 Human ITGA4 ORF Clone (BC080190) Inquiry
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