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ITGA2B


Official Full Name
integrin subunit alpha 2b
Organism
Homo sapiens
Gene ID
3674
Background
This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016]
Synonyms
GT; GT1; GTA; CD41; GP2B; HPA3; CD41B; GPIIb; BDPLT2; BDPLT16; PPP1R93

Cat.No. Product Name Price
SHH321173 shRNA set against Human ITGA2B (NM_000419.3) Inquiry
SHH321177 shRNA set against Mouse ITGA2B (NM_010575.2) Inquiry
SHL181306 shRNA set against Human ITGA2B(NM_000419.3) Inquiry
SHL181324 shRNA set against Mouse Itga2b(NM_010575.2) Inquiry
SHW007030 shRNA set against Danio rerio ITGA2B (NM_001003857) Inquiry
Cat.No. Product Name Price
CDCL184969 Human ITGA2B ORF clone(NM_000419.3) Inquiry
CDCS405651 Human ITGA2B ORF Clone (BC117443) Inquiry
MiUTR1H-05020 ITGA2B miRNA 3'UTR clone Inquiry
MiUTR1M-06132 ITGA2B miRNA 3'UTR clone Inquiry
CDCB168505 Danio rerio ITGA2B ORF Clone (NM_001003857) Inquiry
CDCB195630 Rabbit ITGA2B ORF clone (NM_001082065.1) Inquiry
CDCL121869 Human Itga2b ORF clone (NM_010575.2) Inquiry
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