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ISG15

Official Full Name
ISG15 ubiquitin like modifier
Organism
Homo sapiens
GeneID
9636
Background
The protein encoded by this gene is a ubiquitin-like protein that is conjugated to intracellular target proteins upon activation by interferon-alpha and interferon-beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cell-to-cell signaling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermediate filaments, this protein is sometimes secreted. [provided by RefSeq, Dec 2012]
Synonyms
G1P2; IP17; UCRP; IFI15; IMD38; hUCRP;

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