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IQSEC1

Official Full Name
IQ motif and Sec7 domain ArfGEF 1
Organism
Homo sapiens
GeneID
9922
Background
Predicted to enable protein kinase binding activity. Predicted to be involved in several processes, including positive regulation of focal adhesion disassembly; positive regulation of keratinocyte migration; and regulation of postsynaptic neurotransmitter receptor internalization. Located in nucleolus. Implicated in intellectual developmental disorder with short stature and behavioral abnormalities and lung adenocarcinoma. Biomarker of lung non-small cell carcinoma. [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
BRAG2; GEP100; IDDSSBA; ARFGEP100; ARF-GEP100;

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