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IL12A


Official Full Name
interleukin 12A
Organism
Homo sapiens
Gene ID
3592
Background
This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq, Jul 2008]
Synonyms
P35; CLMF; NFSK; NKSF1; IL-12A

Cat.No. Product Name Price
SHH318165 shRNA set against Human IL12 (NM_001559.2) Inquiry
SHH318169 shRNA set against Mouse IL12 (NM_008354.3) Inquiry
SHH318177 shRNA set against Human IL12A (NM_000882.3) Inquiry
SHH318181 shRNA set against Mouse IL12A (NM_008351.2) Inquiry
SHH318185 shRNA set against Rat IL12A (NM_053390.1) Inquiry
SHL170670 shRNA set against Rat Il12a(NM_053390.1) Inquiry
SHL170814 shRNA set against Mouse Il12a(NM_001159424.1) Inquiry
SHW006084 shRNA set against Chicken IL12A (NM_213588) Inquiry
SHW007523 shRNA set against Danio rerio IL12A (NM_001007107) Inquiry
Cat.No. Product Name Price
CDCL120145 Mouse Il12a ORF clone (NM_001159424.1) Inquiry
CDFG019853 Mouse Il12a cDNA Clone(NM_001159424.1) Inquiry
CDFL006127 Mouse Il12a cDNA Clone(NM_008351.2) Inquiry
CDFR013137 Rat Il12a cDNA Clone(NM_053390.1) Inquiry
MiUTR1M-05966 IL12A miRNA 3'UTR clone Inquiry
MiUTR1R-02622 IL12A miRNA 3'UTR clone Inquiry
MiUTR3H-01514 IL12A miRNA 3'UTR clone Inquiry
CDCB167559 Chicken IL12A ORF Clone (NM_213588) Inquiry
CDCB168998 Danio rerio IL12A ORF Clone (NM_001007107) Inquiry
CDCB188446 Rabbit IL12A ORF clone (XM_008266409.1) Inquiry
CDCL184747 Mouse IL12A ORF clone(NM_008351.2) Inquiry
CDCL184748 Rat IL12A ORF clone(NM_053390.1) Inquiry
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