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IBTK


Official Full Name
inhibitor of Bruton tyrosine kinase
Organism
Homo sapiens
Gene ID
25998
Background
Bruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
Synonyms
BTKI; BTBD26

Cat.No. Product Name Price
SHH316345 shRNA set against Human IBTK (NM_015525.2) Inquiry
SHH316349 shRNA set against Mouse IBTK (NM_001081282.2) Inquiry
Cat.No. Product Name Price
CDFH008926 Human IBTK cDNA Clone(NM_015525.2) Inquiry
MiUTR1H-04774 IBTK miRNA 3'UTR clone Inquiry
CDCB185422 Rabbit IBTK ORF clone (XM_008263147.1) Inquiry
CDCH386446 Mouse IBTK ORF clone(NM_001081282.2) Inquiry
CDCL119123 Mouse IBTK ORF clone (NM_015525.2) Inquiry
CDCS413992 Human IBTK ORF Clone (BC113696) Inquiry
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