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HSD11B1


Official Full Name
hydroxysteroid 11-beta dehydrogenase 1
Organism
Homo sapiens
Gene ID
3290
Background
The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, May 2011]
Synonyms
HDL; 11-DH; HSD11; HSD11B; HSD11L; CORTRD2; SDR26C1; 11-beta-HSD1

Cat.No. Product Name Price
SHH132113 shRNA set against Mouse Hsd11b1(NM_008288.2) Inquiry
SHH132149 shRNA set against Rat Hsd11b1(NM_017080.2) Inquiry
SHH132167 shRNA set against Mouse Hsd11b1(NM_001044751.1) Inquiry
SHH315105 shRNA set against Human HSD11B1 (NM_005525.3) Inquiry
SHH315109 shRNA set against Mouse HSD11B1 (NM_008288.2) Inquiry
SHH315113 shRNA set against Rat HSD11B1 (NM_017080.2) Inquiry
Cat.No. Product Name Price
CDFR011147 Rat Hsd11b1 cDNA Clone(NM_017080.2) Inquiry
MiUTR1M-05800 HSD11B1 miRNA 3'UTR clone Inquiry
MiUTR1M-05801 HSD11B1 miRNA 3'UTR clone Inquiry
MiUTR1R-02510 HSD11B1 miRNA 3'UTR clone Inquiry
MiUTR3H-03584 HSD11B1 miRNA 3'UTR clone Inquiry
MiUTR3H-03585 HSD11B1 miRNA 3'UTR clone Inquiry
CDCB158775 Human HSD11B1 ORF clone (BC012593) Inquiry
CDCB192255 Rabbit HSD11B1 ORF clone (XM_002717540.2) Inquiry
CDCL118481 Mouse Hsd11b1 ORF clone (NM_001044751.1) Inquiry
CDCR245215 Mouse Hsd11b1 ORF Clone(NM_008288.2) Inquiry
CDCR378050 Rat Hsd11b1 ORF Clone(NM_017080.2) Inquiry
CDCS409667 Human HSD11B1 ORF Clone (BC012593) Inquiry
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