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HIST1H2BJ


Official Full Name
H2B clustered histone 11
Organism
Homo sapiens
Gene ID
8970
Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq, Aug 2015]
Synonyms
H2BC11; H2BJ; H2B/r; H2BFR; HIST1H2BJ

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SHH122501 shRNA set against Mouse Hist1h2bj(NM_178198.1) Inquiry
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