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HIRA


Official Full Name
histone cell cycle regulator
Organism
Homo sapiens
Gene ID
7290
Background
This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq, Jul 2008]
Synonyms
TUP1; DGCR1; TUPLE1

Cat.No. Product Name Price
SHH121349 shRNA set against Mouse Hira(NM_010435.2) Inquiry
SHH121331 shRNA set against Human HIRA(NM_003325.3) Inquiry
SHH312329 shRNA set against Human HIRA (NM_003325.3) Inquiry
SHH312333 shRNA set against Mouse HIRA (NM_010435.2) Inquiry
SHH312337 shRNA set against Rat HIRA (NM_001135760.1) Inquiry
SHW004748 shRNA set against Chicken HIRA (NM_204232) Inquiry
Cat.No. Product Name Price
CDCR377224 Rat Hira ORF Clone(NM_001135760.1) Inquiry
CDFH008485 Human HIRA cDNA Clone(NM_003325.3) Inquiry
CDFH008486 Human HIRA cDNA Clone(NM_003325.3) Inquiry
CDFL005686 Mouse Hira cDNA Clone(NM_010435.2) Inquiry
CDFR009801 Rat Hira cDNA Clone(NM_001135760.1) Inquiry
MiUTR1H-04511 HIRA miRNA 3'UTR clone Inquiry
MiUTR1M-05631 HIRA miRNA 3'UTR clone Inquiry
CDCB166223 Chicken HIRA ORF Clone (NM_204232) Inquiry
CDCL117115 Human Hira ORF clone (NM_010435.2) Inquiry
CDCR285397 Human HIRA ORF Clone(NM_003325.3) Inquiry
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