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HDAC5


Official Full Name
histone deacetylase 5
Organism
Homo sapiens
Gene ID
10014
Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
HD5; NY-CO-9

Cat.No. Product Name Price
SHH116363 shRNA set against Human HDAC5(NM_001015053.1) Inquiry
SHH116381 shRNA set against Mouse Hdac5(NM_001077696.1) Inquiry
SHH311005 shRNA set against Human HDAC5 (NM_005474.4) Inquiry
SHH311009 shRNA set against Mouse HDAC5 (NM_010412.3) Inquiry
SHH116399 shRNA set against Mouse Hdac5(NM_010412.3) Inquiry
SHH116417 shRNA set against Human HDAC5(NM_005474.4) Inquiry
SHH311013 shRNA set against Rat HDAC5 (NM_053450.1) Inquiry
Cat.No. Product Name Price
CDCL116307 Mouse Hdac5 ORF clone (NM_001077696.1) Inquiry
CDCR290583 Human HDAC5 ORF Clone(NM_005474.4) Inquiry
CDFH008358 Human HDAC5 cDNA Clone(NM_001015053.1) Inquiry
CDFH008359 Human HDAC5 cDNA Clone(NM_005474.4) Inquiry
MiUTR1H-04417 HDAC5 miRNA 3'UTR clone Inquiry
MiUTR1H-04418 HDAC5 miRNA 3'UTR clone Inquiry
MiUTR1M-05566 HDAC5 miRNA 3'UTR clone Inquiry
MiUTR1M-05567 HDAC5 miRNA 3'UTR clone Inquiry
SKO0129 HDAC5 Validated sgRNA vector Inquiry
CDCB182506 Rabbit HDAC5 ORF clone (XM_002719433.2) Inquiry
CDCL116313 Human HDAC5 ORF clone (NM_001015053.1) Inquiry
CDCR248951 Mouse Hdac5 ORF Clone(NM_010412.3) Inquiry
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