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UBR5

Official Full Name
ubiquitin protein ligase E3 component n-recognin 5
Organism
Homo sapiens
GeneID
51366
Background
This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. [provided by RefSeq, Jul 2008]
Synonyms
DD5; EDD; HYD; EDD1;

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