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HTRA1

Official Full Name
HtrA serine peptidase 1
Organism
Homo sapiens
GeneID
5654
Background
This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7. [provided by RefSeq, Jul 2008]
Synonyms
L56; HtrA; ARMD7; ORF480; PRSS11; CARASIL; CADASIL2;

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