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hnf1ba

Official Full Name
HNF1 homeobox Ba
Organism
Danio rerio
GeneID
792391
Background
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein dimerization activity. Involved in hindbrain development. Acts upstream of or within several processes, including embryonic organ development; hindbrain development; and liver development. Predicted to be active in nucleus. Is expressed in several structures, including digestive system; heart; neural plate; posterior neural keel; and pronephros. Human ortholog(s) of this gene implicated in kidney disease; maturity-onset diabetes of the young type 5; pancreas disease; renal cell carcinoma; and type 2 diabetes mellitus. Orthologous to human HNF1B (HNF1 homeobox B). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
mst; tcf2; hnf1b; vhnf1; chunp6877;

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