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HMGB3

Official Full Name
high mobility group box 3
Organism
Homo sapiens
GeneID
3149
Background
This gene encodes a member of a family of proteins containing one or more high mobility group DNA-binding motifs. The encoded protein plays an important role in maintaining stem cell populations, and may be aberrantly expressed in tumor cells. A mutation in this gene was associated with microphthalmia, syndromic 13. There are numerous pseudogenes of this gene on multiple chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Synonyms
HMG4; HMG-4; HMG2A; HMG-2a;

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