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HLA-DOA


Official Full Name
major histocompatibility complex, class II, DO alpha
Organism
Homo sapiens
Gene ID
3111
Background
HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq, Jul 2008]
Synonyms
HLADZ; HLA-DNA; HLA-DZA

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