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HFE

Official Full Name
homeostatic iron regulator
Organism
Homo sapiens
GeneID
3077
Background
The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. [provided by RefSeq, May 2022]
Synonyms
HH; HFE1; HLA-H; MVCD7; TFQTL2;

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