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HERC3

Official Full Name
HECT and RLD domain containing E3 ubiquitin protein ligase 3
Organism
Homo sapiens
GeneID
8916
Background
This gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012]

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