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hars

Official Full Name
histidyl-tRNA synthetase
Organism
Danio rerio
GeneID
447847
Background
Predicted to enable RNA binding activity; histidine-tRNA ligase activity; and identical protein binding activity. Acts upstream of or within regulation of vasculature development and sprouting angiogenesis. Located in mitochondrion. Is expressed in nervous system; optic cup; optic vesicle; and otic vesicle. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease, axonal type 2W; Perrault syndrome; and Usher syndrome type 3B. Orthologous to several human genes including HARS1 (histidyl-tRNA synthetase 1). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
zgc:92215; im:7136719;

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