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GSTA3


Official Full Name
glutathione S-transferase alpha 3
Organism
Homo sapiens
Gene ID
2940
Background
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
Synonyms
GTA3; GSTA3-3

Cat.No. Product Name Price
SHH308562 shRNA set against Human GSTA3 (NM_000847.4) Inquiry
SHH107219 shRNA set against Rat Gsta3(NM_031509.2) Inquiry
SHH107255 shRNA set against Mouse Gsta3(NM_010356.3) Inquiry
SHH107273 shRNA set against Mouse Gsta3(NM_001077353.1) Inquiry
SHH308566 shRNA set against Mouse GSTA3 (NM_010356.3) Inquiry
SHW000110 shRNA set against Chicken GSTA3 (NM_001001777) Inquiry
SHW005324 shRNA set against Chicken GSTA3 (NM_204818) Inquiry
Cat.No. Product Name Price
CDFR012671 Rat Gsta3 cDNA Clone(NM_031509.2) Inquiry
MiUTR1M-05419 GSTA3 miRNA 3'UTR clone Inquiry
MiUTR1M-05420 GSTA3 miRNA 3'UTR clone Inquiry
MiUTR1R-02316 GSTA3 miRNA 3'UTR clone Inquiry
MiUTR3H-07678 GSTA3 miRNA 3'UTR clone Inquiry
CDCB161585 Chicken GSTA3 ORF Clone (NM_001001777) Inquiry
CDCB166799 Chicken GSTA3 ORF Clone (NM_204818) Inquiry
CDCL115121 Human Gsta3 ORF clone (NM_010356.3) Inquiry
CDCR233906 Mouse Gsta3 ORF Clone(NM_001077353.1) Inquiry
CDCR379704 Rat Gsta3 ORF Clone(NM_031509.2) Inquiry
CDCS405942 Human GSTA3 ORF Clone (BC020619) Inquiry
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