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GRM3


Official Full Name
glutamate metabotropic receptor 3
Organism
Homo sapiens
Gene ID
2913
Background
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. [provided by RefSeq, Jul 2008]
Synonyms
GLUR3; mGlu3; GPRC1C; MGLUR3

Cat.No. Product Name Price
SHH105581 shRNA set against Human GRM3(NM_000840.2) Inquiry
SHH105599 shRNA set against Mouse Grm3(NM_181850.2) Inquiry
SHH308114 shRNA set against Human GRM3 (NM_000840.2) Inquiry
SHH308118 shRNA set against Mouse GRM3 (NM_181850.2) Inquiry
SHH308122 shRNA set against Rat GRM3 (NM_001105712.1) Inquiry
SHW012742 shRNA set against Danio rerio GRM3 (NM_001128343) Inquiry
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OE-PNDC000129 Human GRM3 Nanodisc Inquiry
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CDCL114855 Mouse Grm3 ORF clone (NM_181850.2) Inquiry
CDCR337763 Human GRM3 ORF Clone(NM_000840.2) Inquiry
CDCS405938 Human GRM3 ORF Clone (BC041407) Inquiry
CDFH008069 Human GRM3 cDNA Clone(NM_000840.2) Inquiry
CDFR005302 Rat Grm3 cDNA Clone(NM_001105712.1) Inquiry
MiUTR1H-04291 GRM3 miRNA 3'UTR clone Inquiry
MiUTR1M-05392 GRM3 miRNA 3'UTR clone Inquiry
CDCB174217 Danio rerio GRM3 ORF Clone (NM_001128343) Inquiry
CDCB184058 Rabbit GRM3 ORF clone (XM_002713841.2) Inquiry
CDCR371894 Rat Grm3 ORF Clone(NM_001105712.1) Inquiry
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