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GP5


Official Full Name
glycoprotein V platelet
Organism
Homo sapiens
Gene ID
2814
Background
Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al., 1998 [PubMed 9616133]).[supplied by OMIM, Nov 2010]
Synonyms
GPV; CD42d

Cat.No. Product Name Price
SHH095159 shRNA set against Rat Gp5(NM_012795.2) Inquiry
SHH095167 shRNA set against Human GP5(NM_004488.2) Inquiry
SHH095185 shRNA set against Mouse Gp5(NM_008148.3) Inquiry
SHH305558 shRNA set against Human GP5 (NM_004488.2) Inquiry
SHH305566 shRNA set against Rat GP5 (NM_012795.2) Inquiry
Cat.No. Product Name Price
CDCB190468 Rabbit GP5 ORF clone (XM_008266817.1) Inquiry
CDFL005197 Mouse Gp5 cDNA Clone(NM_008148.3) Inquiry
CDFR010597 Rat Gp5 cDNA Clone(NM_012795.2) Inquiry
MiUTR1H-04152 GP5 miRNA 3'UTR clone Inquiry
MiUTR1M-05255 GP5 miRNA 3'UTR clone Inquiry
MiUTR1R-02197 GP5 miRNA 3'UTR clone Inquiry
CDCR244969 Mouse Gp5 ORF Clone(NM_008148.3) Inquiry
CDCR377655 Rat Gp5 ORF Clone(NM_012795.2) Inquiry
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