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Gm1060

Official Full Name
dynein regulatory complex subunit 1
Organism
Mus musculus
GeneID
381738
Background
Acts upstream of or within several processes, including cilium assembly; determination of left/right symmetry; and single fertilization. Is active in cytosol and sperm flagellum. Is expressed in several structures, including brain; nasal cavity respiratory epithelium; and respiratory system epithelium. Used to study Kartagener syndrome; primary ciliary dyskinesia 21; and visceral heterotaxy. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 21 and spermatogenic failure 80. Orthologous to human DRC1 (dynein regulatory complex subunit 1). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Gm1060; Ccdc164; b2b1654Clo;

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