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GIT2


Official Full Name
GIT ArfGAP 2
Organism
Homo sapiens
Gene ID
9815
Background
This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding. [provided by RefSeq, Sep 2008]
Synonyms
PKL; CAT2; CAT-2

Cat.No. Product Name Price
SHH085331 shRNA set against Mouse Git2(NM_001077359.1) Inquiry
SHH085259 shRNA set against Rat Git2(NM_001005553.1) Inquiry
SHH085277 shRNA set against Mouse Git2(NM_019834.3) Inquiry
SHH085367 shRNA set against Mouse Git2(NM_001077360.1) Inquiry
SHH301270 shRNA set against Human GIT2 (NM_014776.3) Inquiry
SHH301274 shRNA set against Mouse GIT2 (NM_019834.3) Inquiry
SHH301278 shRNA set against Rat GIT2 (NM_001005553.1) Inquiry
SHW004723 shRNA set against Chicken GIT2 (NM_204206) Inquiry
Cat.No. Product Name Price
MiUTR4H-TG03819 GIT2 miRNA 3'UTR clone Inquiry
MiUTR1R-02114 GIT2 miRNA 3'UTR clone Inquiry
MiUTR1M-05048 GIT2 miRNA 3'UTR clone Inquiry
MiUTR1M-05047 GIT2 miRNA 3'UTR clone Inquiry
CDFR001475 Rat Git2 cDNA Clone(NM_001005553.1) Inquiry
CDFL005023 Mouse Git2 cDNA Clone(NM_019834.3) Inquiry
CDFH007580 Human GIT2 cDNA Clone(NM_001135214.1) Inquiry
CDFH007579 Human GIT2 cDNA Clone(NM_001135213.1) Inquiry
MiUTR3H-10095 GIT2 miRNA 3'UTR clone Inquiry
CDCS408071 Human GIT2 ORF Clone (BC014223) Inquiry
CDCR368536 Rat Git2 ORF Clone(NM_001005553.1) Inquiry
CDCR254293 Mouse Git2 ORF Clone(NM_019834.3) Inquiry
CDCL111721 Human GIT2 ORF clone (NM_001135213.1) Inquiry
CDCL111719 Human GIT2 ORF clone (NM_001135214.1) Inquiry
CDCL111717 Human GIT2 ORF clone (NM_139201.2) Inquiry
CDCL111711 Mouse Git2 ORF clone (NM_001077359.1) Inquiry
CDCL111709 Human Git2 ORF clone (NM_001077360.1) Inquiry
CDCB180566 Rabbit GIT2 ORF clone (XM_008249112.1) Inquiry
CDCR314706 Human GIT2 ORF Clone(NM_057169.3) Inquiry
CDCB166198 Chicken GIT2 ORF Clone (NM_204206) Inquiry
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