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GDF5


Official Full Name
growth differentiation factor 5
Organism
Homo sapiens
Gene ID
8200
Background
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations in this gene are associated with acromesomelic dysplasia, brachydactyly, chondrodysplasia, multiple synostoses syndrome, proximal symphalangism, and susceptibility to osteoarthritis. [provided by RefSeq, Aug 2016]
Synonyms
OS5; LAP4; BDA1C; BMP14; CDMP1; LAP-4; SYM1B; SYNS2; BMP-14; DUPANS

Cat.No. Product Name Price
SHH300310 shRNA set against Human GDF5 (NM_000557.2) Inquiry
SHH300314 shRNA set against Mouse GDF5 (NM_008109.2) Inquiry
SHW004853 shRNA set against Chicken GDF5 (NM_204338) Inquiry
Cat.No. Product Name Price
CDFH007464 Human GDF5 cDNA Clone(NM_000557.2) Inquiry
MiUTR1H-03999 GDF5 miRNA 3'UTR clone Inquiry
CDCB156889 Rat GDF5 ORF clone (XM_001066344.2) Inquiry
CDCB166328 Chicken GDF5 ORF Clone (NM_204338) Inquiry
CDCB195008 Rabbit GDF5 ORF clone (NM_001171487.1) Inquiry
CDCL111155 Human GDF5 ORF clone (NM_000557.2) Inquiry
CDCL111157 Human Gdf5 ORF clone (NM_008109.2) Inquiry
CDCS405741 Human GDF5 ORF Clone (BC032495) Inquiry
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