Pages
Products

GALE


Official Full Name
UDP-galactose-4-epimerase
Organism
Homo sapiens
Gene ID
2582
Background
This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and cognitive disability, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Synonyms
THC13; SDR1E1

Cat.No. Product Name Price
SHH075593 shRNA set against Human GALE(NM_000403.3) Inquiry
SHH075557 shRNA set against Rat Gale(NM_080783.2) Inquiry
SHH075575 shRNA set against Mouse Gale(NM_178389.3) Inquiry
SHH298885 shRNA set against Human GALE (NM_000403.3) Inquiry
SHH298889 shRNA set against Mouse GALE (NM_178389.3) Inquiry
SHH298893 shRNA set against Rat GALE (NM_080783.2) Inquiry
SHW009627 shRNA set against Danio rerio GALE (NM_001040299) Inquiry
Cat.No. Product Name Price
CDCB158762 Human GALE ORF clone (BC001273) Inquiry
CDFH007335 Human GALE cDNA Clone(NM_000403.3) Inquiry
CDFH007336 Human GALE cDNA Clone(NM_001008216.1) Inquiry
CDFH007337 Human GALE cDNA Clone(NM_001127621.1) Inquiry
CDFR013842 Rat Gale cDNA Clone(NM_080783.2) Inquiry
MiUTR1H-03932 GALE miRNA 3'UTR clone Inquiry
MiUTR1M-04904 GALE miRNA 3'UTR clone Inquiry
MiUTR1R-02028 GALE miRNA 3'UTR clone Inquiry
CDCB171102 Danio rerio GALE ORF Clone (NM_001040299) Inquiry
CDCB190713 Rabbit GALE ORF clone (XM_002715981.2) Inquiry
CDCL110419 Human Gale ORF clone (NM_178389.3) Inquiry
CDCR336158 Human GALE ORF Clone(NM_000403.3) Inquiry
CDCR340343 Human GALE ORF Clone(NM_001008216.1) Inquiry
CDCR348766 Human GALE ORF Clone(NM_001127621.1) Inquiry
CDCR380876 Rat Gale ORF Clone(NM_080783.2) Inquiry
CDCS405641 Human GALE ORF Clone (BC001273) Inquiry
Cat.No. Product Name Price
CC-547 GALE Easy KO Kit Inquiry
Quick Inquiry