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GAD1


Official Full Name
glutamate decarboxylase 1
Organism
Homo sapiens
Gene ID
2571
Background
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq, Jul 2008]
Synonyms
GAD; SCP; CPSQ1; DEE89

Cat.No. Product Name Price
SHH074837 shRNA set against Human GAD1(NM_000817.2) Inquiry
SHH074855 shRNA set against Rat Gad1(NM_017007.1) Inquiry
SHH074873 shRNA set against Mouse Gad1(NM_008077.4) Inquiry
SHH074891 shRNA set against Human GAD1(NM_013445.3) Inquiry
SHH298665 shRNA set against Human GAD1 (NM_000817.2) Inquiry
SHH298669 shRNA set against Mouse GAD1 (NM_008077.4) Inquiry
SHH298673 shRNA set against Rat GAD1 (NM_017007.1) Inquiry
SHW005418 shRNA set against Chicken GAD1 (NM_204913) Inquiry
SHW015655 shRNA set against Danio rerio GAD1B (NM_194419) Inquiry
Cat.No. Product Name Price
MiUTR1R-02021 GAD1 miRNA 3'UTR clone Inquiry
MiUTR1H-03919 GAD1 miRNA 3'UTR clone Inquiry
MiUTR1H-03918 GAD1 miRNA 3'UTR clone Inquiry
CDCG004817 Mouse GAD1 ORF clone(NM_008077.4) Inquiry
CDFR011077 Rat Gad1 cDNA Clone(NM_017007.1) Inquiry
CDFH007296 Human GAD1 cDNA Clone(NM_013445.3) Inquiry
CDFH007295 Human GAD1 cDNA Clone(NM_000817.2) Inquiry
MiUTR1M-04896 GAD1 miRNA 3'UTR clone Inquiry
CDCS405925 Human GAD1 ORF Clone (BC037780) Inquiry
CDCS405924 Human GAD1 ORF Clone (BC026349) Inquiry
CDCR378120 Rat Gad1 ORF Clone(NM_017007.1) Inquiry
CDCR337751 Human GAD1 ORF Clone(NM_000817.2) Inquiry
CDCR296616 Human GAD1 ORF Clone(NM_013445.3) Inquiry
CDCB190922 Rabbit GAD1 ORF clone (XM_002712277.2) Inquiry
CDCB177130 Danio rerio GAD1B ORF Clone (NM_194419) Inquiry
CDCS405923 Human GAD1 ORF Clone (BC002815) Inquiry
CDCB166893 Chicken GAD1 ORF Clone (NM_204913) Inquiry
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