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GYPC

Official Full Name
glycophorin C (Gerbich blood group)
Organism
Homo sapiens
GeneID
2995
Background
Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
Synonyms
GE; GPC; GPD; GYPD; CD236; PAS-2; CD236R; PAS-2';

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