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GSDMA3

Official Full Name
gasdermin A3
Organism
Mus musculus
GeneID
450219
Background
Enables cardiolipin binding activity and wide pore channel activity. Involved in several processes, including hair follicle development; positive regulation of interleukin-1 beta production; and pyroptotic inflammatory response. Acts upstream of or within several processes, including hair follicle morphogenesis; negative regulation of timing of anagen; and regulation of signal transduction. Located in several cellular components, including cytosol; mitochondrion; and nucleus. Is active in membrane. Is expressed in foregut; hair root sheath; and hair shaft. Orthologous to human GSDMA (gasdermin A). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Gsdma3; Bsk; Dfl; Fgn; Rco2; Rim3; Gsdm3; Gsdm1l; GsdmA-3;

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