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GRK4

Official Full Name
G protein-coupled receptor kinase 4
Organism
Homo sapiens
GeneID
2868
Background
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
Synonyms
IT11; GPRK4; GRK4a; GPRK2L;

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