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grhl2b


Official Full Name
grainyhead-like transcription factor 2b
Organism
Danio rerio
Gene ID
100034503
Background
Enables transcription cis-regulatory region binding activity. Acts upstream of or within apoptotic process involved in morphogenesis; inner ear development; and midbrain-hindbrain boundary morphogenesis. Predicted to be active in nucleus. Is expressed in several structures, including anterior axial hypoblast; midbrain hindbrain boundary neural rod; neurogenic placode; optic vesicle; and posterior lateral line system. Used to study autosomal dominant nonsyndromic deafness. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 28 and posterior polymorphous corneal dystrophy 4. Orthologous to human GRHL2 (grainyhead like transcription factor 2). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
grhl2; si:dkey-21k18.2

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