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GPX6


Official Full Name
glutathione peroxidase 6
Organism
Homo sapiens
Gene ID
257202
Background
The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of hydrogen peroxide, organic hydroperoxides and lipid hydroperoxides, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. Expression of this gene has been observed in embryos and olfactory epithelium; however, the exact function of this gene is not known. This isozyme is a selenoprotein in humans, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. The orthologs of this gene in mouse and rat (and some other species) contain a cysteine (Cys) residue in place of the Sec residue, and their corresponding mRNAs lack SECIS element. [provided by RefSeq, Jul 2017]
Synonyms
GPX5p; GPXP3; GPx-6; GSHPx-6; dJ1186N24; dJ1186N24.1

Cat.No. Product Name Price
SHH102683 shRNA set against Mouse Gpx6(NM_145451.3) Inquiry
SHH102701 shRNA set against Rat Gpx6(NM_147165.1) Inquiry
SHH102719 shRNA set against Human GPX6(NM_182701.1) Inquiry
SHH307418 shRNA set against Human Gpx6 (NM_182701.1) Inquiry
SHH307422 shRNA set against Mouse Gpx6 (NM_145451.3) Inquiry
SHH307426 shRNA set against Rat Gpx6 (NM_147165.1) Inquiry
Cat.No. Product Name Price
CDFG012163 Human GPX6 cDNA Clone(NM_182701.1) Inquiry
CDFR014545 Rat Gpx6 cDNA Clone(NM_147165.1) Inquiry
MiUTR1H-04247 GPX6 miRNA 3'UTR clone Inquiry
MiUTR1M-05350 GPX6 miRNA 3'UTR clone Inquiry
MiUTR1R-02272 GPX6 miRNA 3'UTR clone Inquiry
CDCB192977 Rabbit GPX6 ORF clone (NM_001256906.1) Inquiry
CDCL114457 Mouse GPX6 ORF clone (NM_182701.1) Inquiry
CDCL151058 Human Gpx6 ORF clone (NM_145451.3) Inquiry
CDCR381632 Rat Gpx6 ORF Clone(NM_147165.1) Inquiry
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