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GPR56

Official Full Name
adhesion G protein-coupled receptor G1
Organism
Homo sapiens
GeneID
9289
Background
This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Synonyms
ADGRG1; BFPP; BPPR; GPR56; TM7LN4; TM7XN1; CDCBM14B; CDCBM15A;

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