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GLUD1


Official Full Name
glutamate dehydrogenase 1
Organism
Homo sapiens
Gene ID
2746
Background
This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X. [provided by RefSeq, Jan 2016]
Synonyms
GDH; GDH1; GLUD; hGDH1

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SHW015836 shRNA set against Danio rerio GLUD1B (NM_199545) Inquiry
SHW017741 shRNA set against Danio rerio GLUD1A (NM_212576) Inquiry
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OE-PNDC000245 Human GRID1 Nanodisc Inquiry
Cat.No. Product Name Price
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MiUTR1R-02285 GRID1 miRNA 3'UTR clone Inquiry
MiUTR3H-00873 GLUD1 miRNA 3'UTR clone Inquiry
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CDCB187729 Rabbit GRID1 ORF clone (XM_008269882.1) Inquiry
CDCG009272 Human GLUD1 ORF clone(NM_005271.3) Inquiry
CDCR244282 Mouse Glud1 ORF Clone(NM_008133.4) Inquiry
CDCR245003 Mouse Grid1 ORF Clone(NM_008166.2) Inquiry
CDCR377306 Rat Glud1 ORF Clone(NM_012570.2) Inquiry
CDCR379399 Rat Grid1 ORF Clone(NM_024378.1) Inquiry
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