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GLDC


Official Full Name
glycine decarboxylase
Organism
Homo sapiens
Gene ID
2731
Background
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).[provided by RefSeq, Jan 2010]
Synonyms
GCE; GCE1; GCSP; HYGN1

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CDCB166313 Chicken GLDC ORF Clone (NM_204322) Inquiry
CDCB177318 Danio rerio GLDC ORF Clone (NM_199554) Inquiry
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