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ghra


Official Full Name
growth hormone receptor a
Organism
Danio rerio
Gene ID
100001424
Background
Predicted to enable cytokine binding activity; growth hormone receptor activity; and peptide hormone binding activity. Predicted to be involved in cell surface receptor signaling pathway; positive regulation of cell population proliferation; and positive regulation of receptor signaling pathway via JAK-STAT. Predicted to act upstream of or within endocytosis. Predicted to be located in extracellular region and membrane. Predicted to be part of growth hormone receptor complex. Predicted to be active in cytosol and external side of plasma membrane. Is expressed in several structures, including lens; muscle; notochord; pleuroperitoneal region; and yolk. Human ortholog(s) of this gene implicated in several diseases, including Laron syndrome; familial hypercholesterolemia; isolated growth hormone deficiency; osteoarthritis; and type 2 diabetes mellitus. Orthologous to human GHR (growth hormone receptor). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
ghr; ghr.a; zgc:162141

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CDCB172791 Danio rerio GHRA ORF Clone (NM_001083578) Inquiry
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