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GCDH


Official Full Name
glutaryl-CoA dehydrogenase
Organism
Homo sapiens
Gene ID
2639
Background
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12. [provided by RefSeq, Mar 2013]
Synonyms
GCD; ACAD5

Cat.No. Product Name Price
SHH079463 shRNA set against Human GCDH(NM_000159.2) Inquiry
SHH079477 shRNA set against Human GCDH(NM_013976.2) Inquiry
SHH079479 shRNA set against Mouse Gcdh(NM_008097.2) Inquiry
SHH079497 shRNA set against Human GCDH(NM_000159.2) Inquiry
SHH079501 shRNA set against Human GCDH(NM_013976.2) Inquiry
SHH079517 shRNA set against Mouse Gcdh(NM_001044744.1) Inquiry
SHH299946 shRNA set against Human GCDH (NM_000159.2) Inquiry
SHH299950 shRNA set against Mouse GCDH (NM_008097.2) Inquiry
SHH299954 shRNA set against Rat GCDH (NM_001108896.1) Inquiry
Cat.No. Product Name Price
CDCR375238 Rat Gcdh ORF Clone(NM_001108896.1) Inquiry
CDFH007424 Human GCDH cDNA Clone(NM_000159.2) Inquiry
CDFH007425 Human GCDH cDNA Clone(NM_013976.2) Inquiry
CDFR008463 Rat Gcdh cDNA Clone(NM_001108896.1) Inquiry
MiUTR1H-03979 GCDH miRNA 3'UTR clone Inquiry
MiUTR1H-03980 GCDH miRNA 3'UTR clone Inquiry
MiUTR1M-04971 GCDH miRNA 3'UTR clone Inquiry
MiUTR1M-04972 GCDH miRNA 3'UTR clone Inquiry
CDCB159395 Human GCDH ORF clone (BC002579) Inquiry
CDCB191700 Rabbit GCDH ORF clone (XM_002724235.2) Inquiry
CDCL110971 Mouse Gcdh ORF clone (NM_008097.2) Inquiry
CDCR233763 Mouse Gcdh ORF Clone(NM_001044744.1) Inquiry
CDCR278724 Human GCDH ORF Clone(NM_000159.2) Inquiry
CDCR296688 Human GCDH ORF Clone(NM_013976.2) Inquiry
CDCS405469 Human GCDH ORF Clone (BC002579) Inquiry
Cat.No. Product Name Price
CC-558 GCDH Easy KO Kit Inquiry
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