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GAA


Official Full Name
alpha glucosidase
Organism
Homo sapiens
Gene ID
2548
Background
This gene encodes lysosomal alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. The encoded preproprotein is proteolytically processed to generate multiple intermediate forms and the mature form of the enzyme. Defects in this gene are the cause of glycogen storage disease II, also known as Pompe's disease, which is an autosomal recessive disorder with a broad clinical spectrum. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Synonyms
LYAG

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SHH298301 shRNA set against Mouse GAA (NM_008064.3) Inquiry
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CDCR244788 Mouse Gaa ORF Clone(NM_008064.3) Inquiry
CDCR382146 Rat Gaa ORF Clone(NM_199118.1) Inquiry
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CC-546 GAA Easy KO Kit Inquiry
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