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G6Pdx

Official Full Name
glucose-6-phosphate dehydrogenase X-linked
Organism
Mus musculus
GeneID
14381
Background
Enables glucose-6-phosphate dehydrogenase activity and identical protein binding activity. Involved in pentose-phosphate shunt, oxidative branch. Acts upstream of or within several processes, including NADP biosynthetic process; erythrocyte development; and maintenance of blood vessel diameter homeostasis by renin-angiotensin. Is active in cytosol. Is expressed in several structures, including brain; genitourinary system; immune system; liver; and mammary gland. Used to study favism. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); cerebrovascular disease; favism; malaria (multiple); and neonatal jaundice. Orthologous to human G6PD (glucose-6-phosphate dehydrogenase). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
G6pdx; G28A; G6pd; Gpdx;

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