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G6PC


Official Full Name
glucose-6-phosphatase catalytic subunit 1
Organism
Homo sapiens
Gene ID
2538
Background
Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.[provided by RefSeq, Feb 2011]
Synonyms
G6PC1; G6PC; G6PT; GSD1; GSD1a; G6Pase

Cat.No. Product Name Price
SHH298249 shRNA set against Rat G6PC (NM_013098.2) Inquiry
SHH072659 shRNA set against Mouse G6pc(NM_008061.3) Inquiry
SHH072695 shRNA set against Rat G6pc(NM_013098.2) Inquiry
SHH298241 shRNA set against Human G6PC (NM_000151.3) Inquiry
SHH298245 shRNA set against Mouse G6PC (NM_008061.3) Inquiry
Cat.No. Product Name Price
CDCL110077 Mouse G6pc ORF clone (NM_008061.3) Inquiry
CDFG022381 Mouse G6pc cDNA Clone(BC013448) Inquiry
CDFR010899 Rat G6pc cDNA Clone(NM_013098.2) Inquiry
MiUTR1M-04863 G6PC miRNA 3'UTR clone Inquiry
MiUTR1R-01999 G6PC miRNA 3'UTR clone Inquiry
MiUTR3H-13029 G6PC miRNA 3'UTR clone Inquiry
CDCB195380 Rabbit G6PC ORF clone (XM_002719415.2) Inquiry
CDCR377976 Rat G6pc ORF Clone(NM_013098.2) Inquiry
CDCS405464 Human G6PC ORF Clone (BC130478) Inquiry
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