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FUBP1


Official Full Name
far upstream element binding protein 1
Organism
Homo sapiens
Gene ID
8880
Background
The protein encoded by this gene is a single stranded DNA-binding protein that binds to multiple DNA elements, including the far upstream element (FUSE) located upstream of c-myc. Binding to FUSE occurs on the non-coding strand, and is important to the regulation of c-myc in undifferentiated cells. This protein contains three domains, an amphipathic helix N-terminal domain, a DNA-binding central domain, and a C-terminal transactivation domain that contains three tyrosine-rich motifs. The N-terminal domain is thought to repress the activity of the C-terminal domain. This protein is also thought to bind RNA, and contains 3'-5' helicase activity with in vitro activity on both DNA-DNA and RNA-RNA duplexes. Aberrant expression of this gene has been found in malignant tissues, and this gene is important to neural system and lung development. Binding of this protein to viral RNA is thought to play a role in several viral diseases, including hepatitis C and hand, foot and mouth disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Synonyms
FBP; FUBP; hDH V

Cat.No. Product Name Price
SHH069833 shRNA set against Rat Fubp1(NM_001037653.1) Inquiry
SHH069815 shRNA set against Human FUBP1(NM_003902.3) Inquiry
SHH069851 shRNA set against Mouse Fubp1(NM_057172.3) Inquiry
SHH297621 shRNA set against Human FUBP1 (NM_003902.3) Inquiry
SHH297625 shRNA set against Mouse FUBP1 (NM_057172.3) Inquiry
SHH297629 shRNA set against Rat FUBP1 (NM_001037653.1) Inquiry
SHW000615 shRNA set against Chicken FUBP1 (NM_001006535) Inquiry
SHW018246 shRNA set against Danio rerio FUBP1 (NM_213144) Inquiry
Cat.No. Product Name Price
CDFH007166 Human FUBP1 cDNA Clone(NM_003902.3) Inquiry
CDFL004813 Mouse Fubp1 cDNA Clone(NM_057172.3) Inquiry
CDFR004595 Rat Fubp1 cDNA Clone(NM_001037653.1) Inquiry
MiUTR1H-03872 FUBP1 miRNA 3'UTR clone Inquiry
MiUTR1M-04823 FUBP1 miRNA 3'UTR clone Inquiry
MiUTR1R-01969 FUBP1 miRNA 3'UTR clone Inquiry
CDCB162090 Chicken FUBP1 ORF Clone (NM_001006535) Inquiry
CDCB179721 Danio rerio FUBP1 ORF Clone (NM_213144) Inquiry
CDCB190514 Rabbit FUBP1 ORF clone (XM_008265015.1) Inquiry
CDCL109729 Mouse FUBP1 ORF clone (NM_003902.3) Inquiry
CDCL109735 Human Fubp1 ORF clone (NM_057172.3) Inquiry
CDCR371477 Rat Fubp1 ORF Clone(NM_001037653.1) Inquiry
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